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A secondary aim of the study was to determine if echocardiographic parameters were different between pacing modalities. Dogs were prospectively recruited following implantation of a St.

All dogs were programmed to VDD at study entry. The highest heart rate was programmed as the upper tracking rate for VVIR with a threshold of 2. After three additional months, echocardiography was repeated, the pacing modality was programmed to VDD and ambulatory ECG monitoring was repeated. As the study is ongoing no final conclusions can be made although synchronous VDD pacing appears to more closely approximate sinus rate and have slower atrial rates than asynchronous VVI or VVIR pacing.

All dogs will have completed the study within the next two months at which time final conclusions can be made. Lyngby , Michael H. Clopidogrel is considered mainstay therapy for the prevention of cardiogenic thromboemboli in cats and has been shown to be superior to aspirin. The quantitation of CAM is the first step in determining if cats can consistently metabolize clopidogrel or if significant interindividual variation exists as in humans with genetic polymorphisms of hepatic cytochrome P Furthermore, having an accurate and precise method for measuring the plasma concentration of CAM will allow safer use of clopidogrel by potentially establishing a therapeutic index and by evaluating whether coadministration of drugs like omeprazole inhibit CAM formation in cats.

FDA guidelines to assess accuracy and precision were followed.

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All assays have been previously validated in cats. Morphologic and morphometric assessments were performed using the neutral, traction, flexion and extension images. Nicole LeBlanc , Katherine Scollan. An area on the left lateral thorax was clipped and alcohol was used to remove oils.

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